Did you know major depressive disorder is one of the most common mental disorders in the United States?

Almost 7% of the U.S. population is diagnosed with depression. Tweet >

Clinical depression is a serious condition that negatively affects how a person thinks, feels, and behaves. In contrast to normal sadness, clinical depression is persistent, and significantly interferes with daily life. Untreated, symptoms can last for weeks, months, or years; and if inadequately treated, depression can lead to other health-related issues. Symptoms include: a depressed mood most of the day, every day; diminished interest in daily activities; changes in appetite and sleeping patterns; fatigue; restlessness; anxiety; feelings of worthlessness or helplessness; difficulty concentrating; increased alcohol or drug use; thoughts of death or suicide.

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Madhukar H. Trivedi, M.D. - Brain & Behavior Research Expert on Depression
Madhukar H. Trivedi, M.D.
October 02, 2015
The impact of exercise on reducing excessive sleepiness in depression is linked to certain chemicals, researchers have found. Reporting their findings online...
J. John Mann, M.D. - Brain & behavior research expert on depression and bipolar disorder
J. John Mann, M.D.
September 30, 2015
Ketamine, an anesthetic drug that has been found in experimental studies to rapidly alleviate symptoms of depression, causes a rapid surge in two important...
Alan Rodney Prossin, M.D. - Brain & Behavior research expert on depression
Alan Rodney Prossin, M.D.
September 28, 2015
New research from BBRF-funded scientists shows how a sad mood can change the inflammatory environment in the body, potentially contributing to the process by...
Fernando Sampaio Goes, M.D. - Brain & behavior research expert on depression
Dr. Fernando S. Goes
September 01, 2015
A new study has pinpointed rare genetic variations that are found more commonly in people with early-onset depression than in people unaffected by the disorder...
James A. Bibb, Ph.D. - Brain & behavior research expert on depression & anxiety
James A. Bibb, Ph.D.
August 21, 2015
Researchers have found that by specifically targeting a central signaling pathway in the brain, they can improve the innate behavioral response to stress in...


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