Depression

Did you know major depressive disorder is one of the most common mental disorders in the United States?

Almost 7% of the U.S. population is diagnosed with depression. Tweet >

Clinical depression is a serious condition that negatively affects how a person thinks, feels, and behaves. In contrast to normal sadness, clinical depression is persistent, and significantly interferes with daily life. Untreated, symptoms can last for weeks, months, or years; and if inadequately treated, depression can lead to other health-related issues. Symptoms include: a depressed mood most of the day, every day; diminished interest in daily activities; changes in appetite and sleeping patterns; fatigue; restlessness; anxiety; feelings of worthlessness or helplessness; difficulty concentrating; increased alcohol or drug use; thoughts of death or suicide.

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Mary L. Phillips, M.D. - Brain & Behavior research expert on mental illness
Mary L. Phillips, M.D.
April 15, 2016
Behavioral problems in childhood can sometimes be early symptoms of psychopathology in adulthood. In a new study published February 23, 2016 in Molecular...
Conor Liston, M.D., Ph.D. - Brain & Behavior Research expert on schizophrenia
Conor Liston, M.D., Ph.D.
April 12, 2016
Anhedonia, or the inability to feel pleasure or enjoyment, is a key symptom in several mental illnesses including major depression and schizophrenia. This...
Christoph Kellendonk, Ph.D. - Brain & behavior research expert on mental illness
Christoph Kellendonk, Ph.D.
April 05, 2016
Researchers are investigating the possibility that infections during pregnancy increase the likelihood that the fetus will develop into a person who will have...
Declan M. McLoughlin, Ph.D - Brain & behavior research expert on depression
Declan M. McLoughlin, Ph.D
April 01, 2016
When treating severe depression with electroconvulsive therapy (ECT), using stronger electric charges on just one side of the brain is just as effective as...
Paul Greengard, Ph.D. - Brain & Behavior Research Expert on Depression
Paul Greengard, Ph.D.
November 13, 2015
Blocking a receptor in the brain called mGluR5 is considered a potential strategy for treating a number of disorders, including major depression, Parkinson’s...

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