![FDA Clears SAINT Rapid-Acting Brain Stimulation Approach for Those Suffering From Resistant Major Depression FDA Clears SAINT Rapid-Acting Brain Stimulation Approach for Those Suffering From Resistant Major Depression](/sites/default/files/styles/large/public/field/image/science-abstract-string-1440.jpg?itok=f9ikmcDG)
On September 6, 2022, the U.S. Food and Drug Administration cleared the way for marketing of a rapid-acting brain-stimulation approach for major depressive disorder pioneered by Nolan Williams, M.D…
Read More
![The last decade has seen a vast increase in the use of brain stimulation technologies to reduce symptoms of psychiatric illness. By far the most influential has been TMS, a non-invasive method employing magnets that generate electric fields which are thought to therapeutically alter the activity of neurons and brain circuits involved in depression and other disorders. TMS was pioneered by BBRF Scientific Council member Mark S. George, M.D., who used two early-career BBRF grants to develop the protocol ultimately approved by the FDA in 2009 for the use of TMS in people with treatment-resistant depression. Use of TMS has expanded greatly since then, along with the development of rTMS (in which the magnetic pulses are short and repetitive), and iTBS (in which the duration of treatment sessions is greatly reduced). TMS and its variants are now FDA-approved for use in depression of all kinds as well as OCD and smoking cessation. Trials are being conducted in other disorders, including PTSD and suicidality, whil The last decade has seen a vast increase in the use of brain stimulation technologies to reduce symptoms of psychiatric illness. By far the most influential has been TMS, a non-invasive method employing magnets that generate electric fields which are thought to therapeutically alter the activity of neurons and brain circuits involved in depression and other disorders. TMS was pioneered by BBRF Scientific Council member Mark S. George, M.D., who used two early-career BBRF grants to develop the protocol ul](/sites/default/files/styles/large/public/field/image/image_2022_12_13T15_00_48_042Z.png?itok=NgcQappr)
The last decade has seen a vast increase in the use of brain stimulation technologies to reduce symptoms of psychiatric illness. By far the most influential has been TMS, a non-invasive method…
Read More
![Team Tests Model to Enable More Effective Targeting of Non-Invasive TMS Treatments in Depression Team Tests Model to Enable More Effective Targeting of Non-Invasive TMS Treatments in Depression](/sites/default/files/styles/large/public/field/image/image_2022_12_13T21_25_38_238Z.png?itok=741lj4lo)
TMS (transcranial magnetic stimulation), a form of non-invasive brain stimulation used to treat depression, has shown its ability to reduce symptoms in many thousands of patients in the years since…
Read More
![Positive Preliminary Results in Highly Personalized Deep-Brain Stimulation Therapy for Treatment-Resistant Depression Positive Preliminary Results in Highly Personalized Deep-Brain Stimulation Therapy for Treatment-Resistant Depression](/sites/default/files/styles/large/public/field/image/abstractbackgroundsciencetechnology-1440_5.jpg?itok=bXIaf292)
A research team led in part by two BBRF grantees has reported initial success in using a novel, highly personalized, and technologically advanced treatment approach to relieve symptoms in a single…
Read More
![Study Indicates Brain Lesions and Treatment Targets in Depression Affect the Same Circuitry, Suggesting New Treatment Possibilities Study Indicates Brain Lesions and Treatment Targets in Depression Affect the Same Circuitry, Suggesting New Treatment Possibilities](/sites/default/files/styles/large/public/field/image/brain-circuitry-depression-treatments-1440.jpg?itok=j4plh14C)
Researchers have reported that the brain circuitry underlying depression is the same or similar in a wide variety of patients and circumstances, and that it is similar to circuitry affected when…
Read More