In some youths, frequent mood instability—sudden and unpredictable shifts in emotional states—may precede a "conversion" to bipolar disorder (BD). These sudden shifts in emotions can take various…
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A follow-up study of young adults who were diagnosed years earlier with childhood-onset bipolar disorder suggests that their cognitive flexibility—in many cases already impaired at the time of…
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On May 28th, the U.S. Food and Drug Administration (FDA) approved cariprazine for the treatment of depressive episodes in adults with bipolar I disorder. Sold under the brand name Vraylar, the…
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Cariprazine, a medicine approved by the FDA in 2015 for the treatment of manic episodes in bipolar I disorder, was effective in reducing depressive symptoms in bipolar I disorder patients in a phase…
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A multi-decade study focusing on children of parents diagnosed with bipolar disorder quantifies the risk—24.5%—that they themselves will develop bipolar illness, and suggests a “progressive sequence…
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