Immune System

Study Finds Anhedonia Symptoms Are Especially Vulnerable in Major Depression Patients with High Bodily Inflammation Levels
It has been estimated that one in three people with major depressive disorder (MDD) exhibits low-grade systemic inflammation. That is to say, they chronically show elevated levels of inflammatory… Read More
Evidence That Endocannabinoid Activity May Protect Brain Vasculature, Leading to Stress Resilience
While stress is a well-validated causal factor in anxiety disorders and depression, understanding the mechanisms that confer susceptibility to stress in some people and resilience in others is an… Read More
Study Reveals New Details About Relationship Between Suicidal Ideation/Attempt and Alterations in the Immune System
Inflammation in the body causes physical pain each day for untold millions of people, and in that respect it is a well-known and well-understood medical problem. Much less well understood is the role… Read More
How Immune Activation May Alter the Brain and Cause Depression-Related Behavior During Chronic Social Stress
Extensive research over several decades, some of it led by investigators supported by BBRF, has demonstrated that stress, including psychosocial stress (stress that arises from social interactions)… Read More
Gliosis, an Immune Response to Brain Injury, Is Found in Brains of Recovered COVID Patients With Lasting Depression and Cognitive Symptoms
In the weeks, months, and even years following a COVID infection, it is not uncommon for those who have recovered from the virus’s acute symptoms to be dogged by persistent depressive symptoms. Often… Read More