Fear Memory

Specific Connectivity Changes and Linked Changes in White Matter Are Associated with PTSD Symptom Reduction in Clinical Trial Results
A new analysis of the results of a clinical trial involving the treatment of people diagnosed with PTSD has yielded insights into how the tested treatment affected connectivity in the brain and how… Read More
Imaging Analysis Suggests How Ketamine Treatment Might Have Helped Reduce Chronic PTSD Symptoms in Trial Subjects
A new study has analyzed detailed brain imaging data of individuals with chronic PTSD who were treated in a clinical trial with ketamine. Results suggest that improvements in PTSD symptoms that were… Read More
Experiments in Rodents Suggest Feasibility of Modifying or Erasing Traumatic Fear Memories
Researchers led by BBRF Scientific Council member and 2017 Distinguished Investigator Stephen Maren, Ph.D., report they have demonstrated in animal experiments the ability to retrieve and weaken or… Read More
Brain Circuit Might be Targeted to Inhibit Threat Response in the Presence of a “Safety” Signal
Researchers have discovered a brain circuit that appears to enable both rodents and people to inhibit their threat response in the presence of a learned “safety signal.” The research suggests it may… Read More
Researchers Pinpoint Biological Differences Underlying the Way Males and Females Process Fear Memories
Males and females have different susceptibility to trauma- and stress-related disorders like anxiety and post-traumatic stress disorder (PTSD), past studies have revealed. For instance, women develop… Read More