Machine Learning Is Harnessed To Predict Risk of Opioid Use Disorder
Opioid overdose has become a public health problem of the first magnitude, identified as the cause of death in over 80,000 cases in the U.S. in 2021—about three-fourths of total deaths attributed to… Read More
Large Genome Study Finds a ‘General Addiction Risk Factor’ Commonly Inherited Across Multiple Substance-Use Disorders
In recent years, studies involving large numbers of individuals have identified numerous locations in the human genome where commonly occurring variations in DNA sequence are associated with… Read More
Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients
A clinical trial involving over 500 adults diagnosed with schizophrenia has found that by adding the drug samidorphan to the antipsychotic medicine olanzapine, it was possible to substantially reduce… Read More
Study Makes Case for Rigorous Re-Testing of Opioid Antagonists to Treat Schizophrenia
Trying to assess the value of an idea that first appealed to the research community in the 1970s, a team of investigators has published a careful statistical analysis of 30 past clinical trials in… Read More
A Computer ‘Game’ to Identify Opioid Abuse Patients at High Risk of Relapse
Researchers have tested a game-like computer program that in a clinical study provided a means of determining which patients in an opioid-treatment program were highly vulnerable to relapse in the… Read More