opioids

Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients
A clinical trial involving over 500 adults diagnosed with schizophrenia has found that by adding the drug samidorphan to the antipsychotic medicine olanzapine, it was possible to substantially reduce… Read More
Study Makes Case for Rigorous Re-Testing of Opioid Antagonists to Treat Schizophrenia
Trying to assess the value of an idea that first appealed to the research community in the 1970s, a team of investigators has published a careful statistical analysis of 30 past clinical trials in… Read More
A Computer ‘Game’ to Identify Opioid Abuse Patients at High Risk of Relapse
Researchers have tested a game-like computer program that in a clinical study provided a means of determining which patients in an opioid-treatment program were highly vulnerable to relapse in the… Read More
Opioids, at Very Low Doses, May Provide a New Way to Treat Resistant Depression
One of the most promising new therapy ideas for brain and behavior disorders may at first seem improbable: using opioid-based medicines to reduce the symptoms of depression. Isn’t our society in the… Read More
Study Points to a New Class of Antidepressants
Compounds that target a certain opioid receptor in the brain could be used to develop a new group of antidepressants, researchers reported in a study published in the journal Neuropsychopharmacology… Read More