opioids

Non-Invasive Low-Power Electrical Stimulation Is Shown in Trial to Modulate Brain Circuitry Involved in Regulating Drug Craving in Opioid Addiction

In the continuing search for new and more effective methods of treating addiction, researchers in the U.S. and around the world have been testing various modes of non-invasive brain stimulation,… Read More

Unique Opportunity to Personalize Deep Brain Stimulation for Severe Opioid Use Disorder Yields Highly Specific Target & Clinical Remission in a Patient

Researchers co-led by BBRF grantees have conducted a clinical test of a new way to target deep-brain stimulation (DBS)-based treatments to prevent drug craving and relapse in a patient with… Read More

A Strategy to Sharply Blunt Addictive Reward From Opioids While Retaining Their Pain-Relieving Properties

Since the 1990s, deaths due to opioid overdoses have become a leading cause of death for Americans under age 50. While a portion of these deaths are due to recreational use of opioids, many others… Read More

Machine Learning Is Harnessed To Predict Risk of Opioid Use Disorder

Opioid overdose has become a public health problem of the first magnitude, identified as the cause of death in over 80,000 cases in the U.S. in 2021—about three-fourths of total deaths attributed to… Read More

Large Genome Study Finds a ‘General Addiction Risk Factor’ Commonly Inherited Across Multiple Substance-Use Disorders

In recent years, studies involving large numbers of individuals have identified numerous locations in the human genome where commonly occurring variations in DNA sequence are associated with… Read More

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