Nitrous Oxide (“Laughing Gas”) May Have Rapid-Acting Anti-Suicidal Effects
Newly reported analysis of the results of three small clinical trials indicates that the gas nitrous oxide (N₂O) may have rapid-acting anti-suicidal effects. Nitrous oxide is often called laughing… Read More
Trial Finds Ketamine and ECT About Equally Effective for Most Patients with Resistant Major Depression
In a clinical trial involving hundreds of patients, ketamine has been found to be about as effective as electroconvulsive therapy (ECT) for treatment of major depressive disorder that has not… Read More
Two Signaling Pathways Involved in Regulating Synaptic Plasticity Suggest Novel Targets for Rapid-Acting Antidepressants
Researchers have reported progress in the important effort to explain the rapid antidepressant action of ketamine, and in so doing, have gained insights that may inform the development of other… Read More
Adding Lithium Might Enable Ketamine's Antidepressant Activity in Ketamine-Resistant Patients, Study Suggests
Researchers have published results of experiments in rodents suggesting that lithium, a widely prescribed mood stabilizer, may have value as an adjunct to ketamine therapy in people who suffer from… Read More
Imaging Analysis Suggests How Ketamine Treatment Might Have Helped Reduce Chronic PTSD Symptoms in Trial Subjects
A new study has analyzed detailed brain imaging data of individuals with chronic PTSD who were treated in a clinical trial with ketamine. Results suggest that improvements in PTSD symptoms that were… Read More