Even with the development and FDA approval in recent years of the first rapid-acting antidepressant medicines—to which more than 90 BBRF grants have contributed—the search for novel depression…
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Newly reported analysis of the results of three small clinical trials indicates that the gas nitrous oxide (N₂O) may have rapid-acting anti-suicidal effects.
Nitrous oxide is often called laughing…
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In a clinical trial involving hundreds of patients, ketamine has been found to be about as effective as electroconvulsive therapy (ECT) for treatment of major depressive disorder that has not…
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Researchers have reported progress in the important effort to explain the rapid antidepressant action of ketamine, and in so doing, have gained insights that may inform the development of other…
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Researchers have published results of experiments in rodents suggesting that lithium, a widely prescribed mood stabilizer, may have value as an adjunct to ketamine therapy in people who suffer from…
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