Behavioral Changes in Cocaine Addiction Are Linked to Altered Patterns of Gene Activity in the Striatum
The urgency of opioid abuse and its status as a public health crisis are subjects frequently noted in public discussions and media reports. Cocaine addiction and its impact on public health, while by… Read More
Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse
In the past several decades, the field of addiction research has been revolutionized by new findings about the role of the neurotransmitter dopamine in affecting the brain’s reward pathways. For… Read More
In 2 Trials, Ketamine Plus Behavioral Therapies Helped People with Cocaine and Alcohol Dependencies to Abstain
Although new knowledge about the brain’s reward circuitry has provided insight into the biology of addiction, this has not yet resulted in new treatments. In animal models of addiction, it has been… Read More
Research Showing How Cocaine Addiction Reprograms the Brain Points to New Therapy Targets
New research from the laboratory of Scientific Council member Eric J. Nestler, M.D., Ph.D. marks a significant advance in our understanding of how cocaine addiction affects the brain. It provides a… Read More