![Behavioral Changes in Cocaine Addiction Are Linked to Altered Patterns of Gene Activity in the Striatum Behavioral Changes in Cocaine Addiction Are Linked to Altered Patterns of Gene Activity in the Striatum](/sites/default/files/styles/large/public/field/image/geneticengineering-1440.jpg?itok=SiJE51Vg)
The urgency of opioid abuse and its status as a public health crisis are subjects frequently noted in public discussions and media reports. Cocaine addiction and its impact on public health, while by…
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![Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse](/sites/default/files/styles/large/public/field/image/image_2022_12_13T15_26_16_337Z.png?itok=ljEoeAop)
In the past several decades, the field of addiction research has been revolutionized by new findings about the role of the neurotransmitter dopamine in affecting the brain’s reward pathways. For…
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![In 2 Trials, Ketamine Plus Behavioral Therapies Helped People with Cocaine and Alcohol Dependencies to Abstain In 2 Trials, Ketamine Plus Behavioral Therapies Helped People with Cocaine and Alcohol Dependencies to Abstain](/sites/default/files/styles/large/public/field/image/womanrelaxinginfrontofwindowonchair-1200.jpg?itok=wbhsLcdD)
Although new knowledge about the brain’s reward circuitry has provided insight into the biology of addiction, this has not yet resulted in new treatments. In animal models of addiction, it has been…
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![Research Showing How Cocaine Addiction Reprograms the Brain Points to New Therapy Targets](/sites/default/files/styles/large/public/field/image/abstractwhitelight-1440_0.jpg?itok=FXqd2GG6)
New research from the laboratory of Scientific Council member Eric J. Nestler, M.D., Ph.D. marks a significant advance in our understanding of how cocaine addiction affects the brain. It provides a…
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