Substance Abuse

Alcohol-Regulating Hormone Delivered in Combination With GLP-1 Drug Could Have Potential Application in Alcohol Use Disorder, Animal Study Suggests
Researchers led by a BBRF grantee report new research extending knowledge about how a naturally occurring hormone called FGF21 helps to regulate alcohol consumption. Using a synthetic analogue of the… Read More
A Possible Biomarker for Cocaine Misuse and a Novel Treatment for Cocaine Addiction Based on Compound in Rosemary
Researchers led by 2017 BBRF Young Investigator Kevin T. Beier, Ph.D., have discovered a way to predict individual behavioral responses to cocaine in mice never exposed to the drug, and have also… Read More
Alcohol Use Worsens Bipolar Symptoms, Study Finds
Bipolar disorder (BD) is characterized by extreme mood swings. About half of people with BD also struggle with alcohol use problems. Both conditions are harmful on their own, but when they happen… Read More
Functional Connectivity Signature for Cocaine Use Disorder and Response to rTMS Brain Stimulation Therapy Is Identified
Researchers have identified a robust functional connectivity brain signature that can accurately characterize neural circuit abnormalities in cocaine use disorder (CUD). The signature can, in turn,… Read More
Probing the Role of Impulsive Behaviors in Alcohol Misuse and Suicidality
Heavy drinking and the problematic use of alcohol are widely thought to be relevant factors in assessing an individual’s risk for suicidal behavior. It has been the role of research to investigate… Read More