brain circuits

In Clinical Test, TMS Targeted Comorbid Depression and Anxiety Symptoms Separately, With Precision-Psychiatry Implications
Many psychiatric disorders are what doctors call “comorbid”—they co-occur with other disorders, whether other brain-based disorders or those affecting other parts of the body. Depression, for example… Read More
Researchers Trace How Ketamine Acts on Specific Brain Circuits and Synapses to Relieve Anhedonia
Researchers have published a highly detailed account of a mechanism through which ketamine, a rapid-acting antidepressant, alters plasticity, or the strength of connections between neurons, and in so… Read More
A 'Common Causal Circuit' in Depression with Possible Therapeutic Implications
If you want to cure an illness, you try to understand its underlying cause or causes, as a precondition for modifying, reducing, or eliminating them. That, in highly simplified terms, is one of the… Read More
Researchers Identify a Neural Signature Centrally Important in Restructuring Negative Self-Beliefs
In a range of psychiatric conditions, notably including depression, eating disorders, and social anxiety disorder, many who suffer have persistent negative beliefs about themselves—for example, that… Read More
Study Indicates Brain Lesions and Treatment Targets in Depression Affect the Same Circuitry, Suggesting New Treatment Possibilities
Researchers have reported that the brain circuitry underlying depression is the same or similar in a wide variety of patients and circumstances, and that it is similar to circuitry affected when… Read More