A Medicine That Treats Mania Also Shows Effectiveness in Treating Depression in Bipolar Disorder
Cariprazine, a medicine approved by the FDA in 2015 for the treatment of manic episodes in bipolar I disorder, was effective in reducing depressive symptoms in bipolar I disorder patients in a phase… Read More
Machine-learning Helped Identify Newly Diagnosed Schizophrenia Patients and Predicted Treatment Response
Using machine-learning techniques to analyze functional imaging data, a team of Foundation-supported researchers reports that it was able to identify the presence of schizophrenia in 78 percent of a… Read More
Genetic Variations Reveal Which Patients Will Have Cognitive Benefits
Antipsychotic medications are a cornerstone of treatment for schizophrenia and related disorders. They prevent hallucinations and delusions for most people, and for some, they also help reduce the… Read More
Molecular Picture Points the Way to Better Antipsychotic Medications
A new high-resolution image of the antipsychotic drug risperidone (Risperdal) bound to the brain receptor through which it exerts its effects could help researchers design safer and more effective… Read More
New Class of Drugs Shows Promise for the Treatment of Schizophrenia
By inhibiting a previously untargeted nerve-cell receptor in the brain, researchers have discovered a new class of compounds that may be useful in the treatment of schizophrenia. In animal models of… Read More