![Lumateperone, an Antipsychotic, is Tested in a Phase 3 Trial for Major Depressive Episodes in Bipolar I and II Disorders Lumateperone, an Antipsychotic, is Tested in a Phase 3 Trial for Major Depressive Episodes in Bipolar I and II Disorders](/sites/default/files/styles/large/public/field/image/image_2022_12_14T15_39_18_039Z.png?itok=4eJ1BFQF)
An international team of researchers has reported positive results in a phase 3 clinical trial of a drug to treat depressive episodes in patients with bipolar I and bipolar II disorder.
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![Study Links Schizophrenia Medicines’ Anticholinergic Impact to Risk of Cognitive Impairment Study Links Schizophrenia Medicines’ Anticholinergic Impact to Risk of Cognitive Impairment](/sites/default/files/styles/large/public/field/image/scienceabstractbrainpatterns-1440.jpg?itok=XQHn1JHu)
An important study led by BBRF grantees has closely examined a commonplace pharmacologic property of many antipsychotic and other medications commonly prescribed to people with chronic schizophrenia…
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![Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients](/sites/default/files/styles/large/public/field/image/young-man-checking-weight-1440.jpg?itok=ZIVsr55O)
A clinical trial involving over 500 adults diagnosed with schizophrenia has found that by adding the drug samidorphan to the antipsychotic medicine olanzapine, it was possible to substantially reduce…
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![Drugs Targeting the Glutamate System Warrant Continued Development for Schizophrenia, Study Finds Drugs Targeting the Glutamate System Warrant Continued Development for Schizophrenia, Study Finds](/sites/default/files/styles/large/public/field/image/molecule-drug-abstract-1440.jpg?itok=DeEVeAIe)
In the continuing effort to develop new medicines to treat schizophrenia, a team led by BBRF Scientific Council member Jeffrey Lieberman, M.D., and including nine other Council Members, BBRF grantees…
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![Study Finds Changes in the Treatment of Bipolar Disorder Over 20 Years Study Finds Changes in the Treatment of Bipolar Disorder Over 20 Years](/sites/default/files/styles/large/public/field/image/maturemanthinking-1440.png?itok=3XTS2UqO)
A study covering the 20 years between 1997 and 2016 shows that substantial changes have occurred in the way doctors are treating outpatients diagnosed with bipolar disorder.
Among a number of…
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