25 Years of Breakthroughs

Development of TMS for Treatment-Resistant Depression
With the help of a Young Investigator Grant, Scientific Council Member Mark S. George, M.D. developed Transcranial Magnetic Stimulation (TMS), a new kind of non-invasive brain stimulation as an… Read More
Discovery of Important Genetic Links to Schizophrenia
In 2008, Foundation Scientific Council Member Mary-Claire King, Ph.D. from the University of Washington—widely known for her discovery of a mutation in a gene she named BRCA1 that led to powerful… Read More
Rapid-Acting Antidepressant Heralded as Biggest Breakthrough in Depression Research in 50 years
Carlos A. Zarate, Jr., M.D., of the National Institute of Mental Health used a 2005 Foundation Independent Investigator Grant to further studies on what is being heralded by experts as the biggest… Read More
Optogenetics: Decoding Brain Circuitry and How it Links to Behavior
Karl Deisseroth, M.D., Ph.D., used his 2005 NARSAD Young Investigator Grant to develop optogenetics, a new technology that has revolutionized systems neuroscience by providing precise control over… Read More
Identification of Brain Signaling Mechanism Opens Pathway for Development of Novel Treatments for Mental Illness
Francis S. Lee, M.D., Ph.D., of Weill Cornell Medical College, was the recipient of two Foundation Young Investigator Grants (in 2005 and 2002) that supported research on growth factors called NGF (… Read More