Schizophrenia

Did you know that schizophrenia affects more than 1 percent of the world's population?

See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

learn more about schizophrenia

Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

 

Zakharenko, M.D., Ph.D. - Brain & Behavior Research Expert on Schizophrenia
Zakharenko, M.D., Ph.D.
January 19, 2017
In a schizophrenia-related disorder known as 22q11.2 deletion syndrome (22q11DS), altered activity along a single molecular pathway can lead to disruptions in...
Daniel Geschwind, Ph.D. - Brain & Behavior Research Expert on Schizophrenia
Daniel Geschwind, Ph.D.
January 10, 2017
A new study implicates two cellular pathways in schizophrenia risk that haven’t been well supported by genetic evidence before. They involve processes related...
Pamela B. Sklar, M.D., Ph.D. - Brain & Behavior Research Expert on Schizophrenia
Pamela B. Sklar, M.D., Ph.D.
November 17, 2016
Researchers have identified nearly 700 genes whose activity levels differ in the brains of people with schizophrenia compared to individuals without the...
 Luis de Lecea, Ph.D. - Brain & behavior research expert on depression
Luis de Lecea, Ph.D.
November 02, 2016
New experiments show that brain cells called VTA dopaminergic neurons are directly responsible for causing and maintaining wakefulness in mice. When these...
James F. Gusella, Ph.D. - Brain & Behavior Research Expert on autism
James F. Gusella, Ph.D.
September 30, 2016
From The Quarterly, September 2016 Genetic abnormalities called copy number variations (CNVs) are thought to be among the most common causes of...

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