Did you know that schizophrenia affects more than 1 percent of the world's population?

See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

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Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research


Alessandro Usiello, Ph.D. - Brain & behavior research expert schizophrenia
Alessandro Usiello, Ph.D.
March 10, 2015
New research by Foundation-funded scientists sheds light on a problem in brain biochemistry that scientists have previously associated with schizophrenia. The...
Kevin Spencer, Ph.D. - Brain & behavior research expert on schziophrenia
Kevin Spencer, Ph.D.
February 05, 2015
A new study has found that abnormal brain activity in people with schizophrenia mirrors similar irregular activity seen in animal models of the disorder. The...
Gerome Breen, Ph.D. - Brain & behavior research expert on schizophrenia
Gerome Breen, Ph.D.
January 30, 2015
Over the past five years, researchers have begun to find the changes in DNA that increase risk for psychiatric disorders. It turns out there is no shortage of...
Patrick F. Sullivan, M.D. - Brain & behavior research expert on schizophrenia
Patrick F. Sullivan, M.D.
January 22, 2015
Bringing Scientists Together to Solve the Mystery of Schizophrenia’s Causation From The Quarterly, Winter 2015 As a psychiatric geneticist, Dr. Sullivan works...
Anissa Abi-Dargham, M.D. - Brain & behavior research expert on schizophrenia
Anissa Abi-Dargham, M.D.
January 22, 2015
From The Quarterly, Winter 2015 For the first time, researchers have shown in a clinical trial that a chemical called a D1 agonist can reduce “working memory”...


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