Did you know that schizophrenia affects more than 1 percent of the world's population?

See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

learn more about schizophrenia

Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research


Paul F. Worley, M.D. - Brain & behavior research expert on schizophrenia
Paul F. Worley, M.D.
May 18, 2015
Researchers have found that the protein encoded by a gene linked with cognition (thinking) responds to existing drug compounds. This discovery points to a...
Joseph Gogos, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Dr. Joseph Gogos
May 11, 2015
The loss of a small piece of chromosome 22 leads to a developmental disorder known as 22q11.2 deletion or DiGeorge syndrome that is characterized by...
Bo Li, Ph.D. - Brain and behavior research expert on schizophrenia
Bo Li, Ph.D.
April 24, 2015
For some years, scientists have had evidence that in schizophrenia, communication between the brain’s PFC, or prefrontal cortex (the seat of higher cognitive...
Adam J. Savitz, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Adam J. Savitz, M.D., Ph.D.
April 21, 2015
An injectable antipsychotic medication whose effects last for three months has successfully delayed the return of schizophrenia symptoms, researchers have...
Xiaodong Zhang, Ph.D. - Brain & behavior research expert on schizophrenia
Xiaodong Zhang, Ph.D.
April 13, 2015
Using a mouse model, scientists have found that the steroid pregnenolone sulfate reduces both behavioral and cognitive symptoms like those seen in...


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