Brain Matters
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A RESEARCHER’S PERSPECTIVE: What Genetics Is Telling Us About Substance Use Disorders

Dr. Sandra Sanchez-Roige explains how large-scale studies of genome variations have identified risk locations for substance use disorders. She also discusses the importance of converting these signals from the genome into biological understanding of mechanisms and vulnerabilities which may

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ECT, MST, and Other Neuromodulation Therapies to Relieve Severe Psychiatric Illness

Dr. Sarah Lisanby has been deeply involved in developing and improving the safety of life-saving neuromodulatory treatments including electroconvulsive therapy (ECT) and magnetic seizure therapy (MST) for severe psychiatric illness.

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‘Brains Within Brains’: Organoid Experiments Show How Pathologies  Emerge in the Developing Brain

A stem cell-based technology provides a unique window on illnesses such as autism and schizophrenia.

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A RESEARCHER’S PERSPECTIVE: What Can We Do When Medicine is Not Enough in the Treatment of Schizophrenia?

Dr. Dawn Velligan discusses ways in which she helps schizophrenia patients handle symptoms that are not resolved by medications.

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Harnessing Memory’s Malleability to ‘Rewrite’ Fear and Other Negative Memories

Dr. Steve Ramirez is revealing where memories “live” in the brain, and explores how traumatic memories might be therapeutically modified.

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A RESEARCHER'S PERSPECTIVE: We Are Witnessing a Revolution in Brain Stimulation

Dr. Mark S. George, a pioneer in the field, explains how TMS and related non-invasive brain stimulation technologies are changing the face of psychiatry.

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A New Approach to Treating Cognitive Deficits in Schizophrenia

Dr. Vikaas Sohal and colleagues have used advanced technologies to discover biological processes that are likely involved in causing cognitive dysfunction in schizophrenia. The road to bold new treatments is being paved with this new knowledge.

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Rethinking Eating Disorders

Eating Disorders (EDs) are among the most prevalent psychiatric disorders yet also among the most misunderstood. Dr. Cynthia Bulik, a BBRF Distinguished Investigator, explains her research indicating that anorexia nervosa, the most deadly ED, is also a disorder of the body's metabolic system.

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Highly Individualized Deep-Brain Stimulation Helps a Patient With Severe Treatment-Resistant Depression

We write about a novel idea to address brain-based disorders that has moved from theory to bedside in only 3 years. Called closed-loop neuromodulation, it involves using electrical stimulation—delivered via an implanted deep-brain stimulation (DBS) device—at a precise location in the brain. The

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How Pandemic-Related Stress Affects Families, Parenting, and Child Mental Health

Research on COVID’s impacts indicates how the pandemic is affecting families and child mental health, as well as how racial and socioeconomic factors can exacerbate risk and pose obstacles to care for those who are underserved by the healthcare system.

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