BBRF-funded researchers search for ways of harnessing potentially therapeutic effects of psychedelic drugs while minimizing or eliminating hallucinations and other unwanted side effects.

Dr. Helen Blair Simpson, a renowned expert on #OCD, explains how clinical trials have clarified which treatments are most effective, and how research is trying to improve upon them.

A 5-time BBRF grantee made discoveries that helped lead to a drug for tardive dyskinesia and genetic tests that match patients with medications most likely to help them.

Starting with problems faced by psychiatric patients, Dr. Akira Sawa and colleagues conduct research in the lab that seeks to bring solutions back to the clinic—a process known as “reverse translation.”

Dr. Scott Russo and colleagues are demonstrating how stress can cause pro-inflammatory immune cells that are manufactured outside the brain—in the body’s “periphery”—to invade the brain and adversely impact behavior

Dr. Sarah Sperry’s finding of considerable “mood instability” between major episodes of depression and mania/hypomania in bipolar disorder could lead to care approaches that may improve patients’ Lives.

Dr. Sandra Sanchez-Roige explains how large-scale studies of genome variations have identified risk locations for substance use disorders. She also discusses the importance of converting these signals from the genome into biological understanding of mechanisms and vulnerabilities which may

Dr. Sarah Lisanby has been deeply involved in developing and improving the safety of life-saving neuromodulatory treatments including electroconvulsive therapy (ECT) and magnetic seizure therapy (MST) for severe psychiatric illness.

A stem cell-based technology provides a unique window on illnesses such as autism and schizophrenia.

Dr. Dawn Velligan discusses ways in which she helps schizophrenia patients handle symptoms that are not resolved by medications.