Brain Matters
Blog

How Stress-Related Immune Activation May Alter the Brain and Impair Behavior

Dr. Scott Russo and colleagues are demonstrating how stress can cause pro-inflammatory immune cells that are manufactured outside the brain—in the body’s “periphery”—to invade the brain and adversely impact behavior

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A Precision-Health Approach to Bipolar Disorder

Dr. Sarah Sperry’s finding of considerable “mood instability” between major episodes of depression and mania/hypomania in bipolar disorder could lead to care approaches that may improve patients’ Lives.

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A RESEARCHER’S PERSPECTIVE: What Genetics Is Telling Us About Substance Use Disorders

Dr. Sandra Sanchez-Roige explains how large-scale studies of genome variations have identified risk locations for substance use disorders. She also discusses the importance of converting these signals from the genome into biological understanding of mechanisms and vulnerabilities which may

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ECT, MST, and Other Neuromodulation Therapies to Relieve Severe Psychiatric Illness

Dr. Sarah Lisanby has been deeply involved in developing and improving the safety of life-saving neuromodulatory treatments including electroconvulsive therapy (ECT) and magnetic seizure therapy (MST) for severe psychiatric illness.

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‘Brains Within Brains’: Organoid Experiments Show How Pathologies  Emerge in the Developing Brain

A stem cell-based technology provides a unique window on illnesses such as autism and schizophrenia.

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A RESEARCHER’S PERSPECTIVE: What Can We Do When Medicine is Not Enough in the Treatment of Schizophrenia?

Dr. Dawn Velligan discusses ways in which she helps schizophrenia patients handle symptoms that are not resolved by medications.

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Harnessing Memory’s Malleability to ‘Rewrite’ Fear and Other Negative Memories

Dr. Steve Ramirez is revealing where memories “live” in the brain, and explores how traumatic memories might be therapeutically modified.

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A RESEARCHER'S PERSPECTIVE: We Are Witnessing a Revolution in Brain Stimulation

Dr. Mark S. George, a pioneer in the field, explains how TMS and related non-invasive brain stimulation technologies are changing the face of psychiatry.

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A New Approach to Treating Cognitive Deficits in Schizophrenia

Dr. Vikaas Sohal and colleagues have used advanced technologies to discover biological processes that are likely involved in causing cognitive dysfunction in schizophrenia. The road to bold new treatments is being paved with this new knowledge.

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Rethinking Eating Disorders

Eating Disorders (EDs) are among the most prevalent psychiatric disorders yet also among the most misunderstood. Dr. Cynthia Bulik, a BBRF Distinguished Investigator, explains her research indicating that anorexia nervosa, the most deadly ED, is also a disorder of the body's metabolic system.

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