Dr. Rakic’s focus is the development of the cerebral cortex and the regulation of neuron production and cell interactions during their migration to the cerebral cortex. He and his colleagues have identified and characterized a number of genes and molecules involved in regulating neuron proliferation, migration, differentiation and death. Dr. Rakic looks at the impact of both genetic and environmental factors on cell migration and his studies in various mammalian species have led to new hypotheses of cortical development and evolution. Additionally his laboratory studies synaptogenesis and the emergence of transmitters and receptors in cortical microcircuitry to provide a framework for understanding human brain development and the pathogenesis of congenital disorders of higher brain functions.

Dr. Rakic graduated with a degree in medicine from the University of Belgrade in Serbia then embarked on a career as a neurosurgeon. He also received a Ph.D. from Belgrade University. His research career began in 1962, with a fellowship at Harvard University.