Dr. Li’s lab focuses on developing novel animal models for neuropsychiatric disorders, such as depression and PTSD, to uncover new molecular targets and therapeutic avenues. Specifically, they investigate neuronal molecular biomarkers modulated by innovative drugs for treating depression and anxiety, as well as seek to develop proactive coping strategies for stress. Their goal is to pinpoint which neurons and molecules can be targeted to alleviate disease symptoms. By elucidating the cellular mechanisms of therapeutic drugs in the brain, the lab aims to enhance drug specificity and minimize adverse effects. It is hoped that this foundational understanding will ultimately guide the design of optimized treatments with improved efficacy and tolerability.