James W. Murrough, M.D., Ph.D.

Scientific Council Member (Joined 2025)
2009 Young Investigator Grant
James W. Murrough, M.D., Ph.D.
Vice Chair for Clinical Research
Professor of Psychiatry and Neuroscience
Icahn School of Medicine at Mount Sinai
Dr. James Murrough is Professor of Psychiatry and Neuroscience, Vice Chair for Clinical Research, and Director of the Depression and Anxiety Center for Discovery and Treatment in the Department of Psychiatry at the Icahn School of Medicine at Mount Sinai in New York. Dr. Murrough is internationally known for his research in depression, anxiety, and posttraumatic stress disorder (PTSD). He has made major contributions to the fields of biological psychiatry and clinical neuroscience, including work advancing ketamine for treatment-resistant depression (TRD) and PTSD. He led a series of studies to advance a completely new molecular target in the brain – the KCNQ (Kv7) potassium channel – for the treatment of depression. Dr. Murrough is the recipient of the Joel Elkes Research Award from the American College of Neuropsychopharmacology and the A.E. Bennett Award from the Society of Biological Psychiatry. He is an active member of the scientific community and an avid mentor to trainees and junior faculty.
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