Mathieu Wolff, Ph.D., University of Bordeaux, France, will investigate brain areas possibly involved in generating cognitive symptoms of schizophrenia, which are not sufficiently relieved by current treatment options. Dr. Wolff will focus on the brain’s medial prefrontal cortex and hippocampus. The team will interfere with cells that connect to those regions and then test for any resulting changes in the activity of both brain regions. They will also test for any resulting cognitive impairment and try to reverse the disruption to the target group of cells. Their findings will help determine the role, and potential therapeutic value, of these cells in schizophrenia.