What’s New with TMS for Depression and Other Brain Diseases

Tuesday, April 10, 2018
What’s New with TMS for Depression and Other Brain Diseases

In 2008, the FDA approved daily Repetitive Transcranial Magnetic Stimulation (rTMS) for treating depression. Lots of research since then, (some BBRF funded) has now expanded what we know and improved how we use TMS. This talk will cover the latest updates for depression (accelerated forms, new pulse frequencies, maintenance treatment) as well as rTMS in other diseases, not yet FDA approved, like OCD, substance abuse, and autism.

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Presented by 
Mark S. George, M.D.
Mark S. George, M.D.
Medical University of South Carolina

Distinguished Professor of Psychiatry, Radiology and Neuroscience

Founding Director, Center for Advanced Imaging Research

Director, Brain Stimulation Laboratory, Psychiatry

Scientific Council Member (joined 2007)

2008 Falcone Prize for Outstanding Achievement in Affective Disorders Research (Colvin Prize)

1998 Independent Investigator Grant

1996 Young Investigator Grant


Dr. George pioneered the use of TMS as a probe of mood-regulating neuronal circuits, conducting some of the first clinical trials of TMS as a treatment for persistent depression, which was FDA-approved in 2008. This work stemmed from his research with fellow Scientific Council Member Robert M. Post, M.D., at the NIMH, where he was one of the first to use functional imaging to assess brain changes associated with normal emotions and those that occur in depression and mania. In 1995, at the Medical University of South Carolina, he founded the functional neuroimaging division and brain stimulation laboratories, now known as the Center for Advanced Imaging Research. He went on to pioneer another treatment for resistant depression, VNS, also recently FDA-approved.

Dr. George received his bachelor of science degree from Davidson College and his M.D. from the Medical University of South Carolina.

Moderated by
Jeffrey Borenstein, M.D.
Brain & Behavior Research Foundation

Jeffrey Borenstein, M.D., serves as the President & CEO of the Brain & Behavior Research Foundation, the largest private funder of mental health research grants. Dr. Borenstein developed the Emmy-nominated public television program “Healthy Minds,” and serves as host and executive producer of the series. The program, broadcast nationwide, is available online, and focuses on topics in psychiatry in order to educate the public, reduce stigma and offer a message of hope. Dr. Borenstein served as Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association from 2012 - 2023.

Dr. Borenstein is a Fellow of the New York Academy of Medicine and serves as the Chair of the Section of Psychiatry at the Academy. He also has served as the President of the New York State Psychiatric Association. Dr. Borenstein earned his undergraduate degree at Harvard and his medical degree at New York University.