Using Neuroscience to Evaluate and Guide Treatment for Pediatric Mood Disorders

Tuesday, May 12, 2020
Using Neuroscience to Evaluate and Guide Treatment for Pediatric Mood Disorders

Research in early onset mood disorders is geared towards using neuroscience to develop interventions that alleviate symptoms, promote healthy brain development, and treat behavioral and emotional difficulties as soon as they arise. This webinar considers the promise of utilizing neuroscience tools to aim for reliable and lasting improvements in symptoms for a large number of children and adolescents who experience a broad spectrum of mood problems. The presentation considers the importance of understanding and leveraging the placebo effect and measuring mechanisms of change, both in the way that treatments are configured and in the way that future clinical trials are designed.

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Presented by 
Manpreet Kaur Singh, M.D. M.S.
Manpreet Kaur Singh, M.D. M.S.
Stanford University School of Medicine

Associate Professor of Psychiatry and Behavioral Sciences

Director, Pediatric Mood Disorders Program

2016 Independent Invesitgator Grant

2008 Young Investigator Grant


Manpreet Singh, M.D., Stanford University, will explore the potential negative side effects of antidepressant medication given to youth at high risk for psychiatric disorders. In youths with emotional dysregulation, side effects have been noted including irritability, agitation, elevated mood. For some youth, these adverse events lead to the development of lifelong psychiatric disorders such as bipolar disorder (BD). Looking at youth with family histories of BD, Dr. Singh will investigate how antidepressant use, combined with typical psychotherapy, alters brain activity and triggers negative side effects.

Moderated by 
Jeffrey Borenstein, M.D.
Brain & Behavior Research Foundation

President and CEO


Jeffrey Borenstein, M.D., serves as the President & CEO of the Brain & Behavior Research Foundation, the largest private funder of mental health research grants. Dr. Borenstein developed the Emmy-nominated public television program “Healthy Minds,” and serves as host and executive producer of the series. The program, broadcast nationwide, is available online, and focuses on topics in psychiatry in order to educate the public, reduce stigma and offer a message of hope. Dr. Borenstein also serves as Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association.

Dr. Borenstein is a Fellow of the New York Academy of Medicine and serves as the Chair of the Section of Psychiatry at the Academy. He also has served as the President of the New York State Psychiatric Association. Dr. Borenstein earned his undergraduate degree at Harvard and his medical degree at New York University.