Therapeutic Targeting of the Microbiome for Neurodevelopmental Disorders

Tuesday, February 14, 2023
Therapeutic Targeting of the Microbiome for Neurodevelopmental Disorders

Traditionally, variation in the genetic code was thought to be the sole cause of neurodevelopmental disorders. However, there is growing consensus behind a ‘two hit’ hypothesis, wherein a secondary environmental influence initiates changes during development that contribute to brain and behavioral dysfunction in genetically predisposed children. Our lab focuses on understanding how environmental factors that disrupt the maternal gut microbiome and its remodeling during pregnancy impact neurodevelopment and risk for neurodevelopmental disorders in descendant generations. We are also investigating the therapeutic potential of targeting the maternal gut microbiome to reduce risk for neurodevelompental disorders in offspring.

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Moderated by
Jeffrey Borenstein, M.D.
Brain & Behavior Research Foundation

Jeffrey Borenstein, M.D., serves as the President & CEO of the Brain & Behavior Research Foundation, the largest private funder of mental health research grants. Dr. Borenstein developed the Emmy-nominated public television program “Healthy Minds,” and serves as host and executive producer of the series. The program, broadcast nationwide, is available online, and focuses on topics in psychiatry in order to educate the public, reduce stigma and offer a message of hope. Dr. Borenstein served as Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association from 2012 - 2023.

Dr. Borenstein is a Fellow of the New York Academy of Medicine and serves as the Chair of the Section of Psychiatry at the Academy. He also has served as the President of the New York State Psychiatric Association. Dr. Borenstein earned his undergraduate degree at Harvard and his medical degree at New York University.