Bipolar Disorder: Harnessing Brain Plasticity for Improved Overall Outcomes

Tuesday, April 16, 2013
Bipolar Disorder: Harnessing Brain Plasticity for Improved Overall Outcomes

Watch Video Recording:

Presented by 
Husseini K. Manji, M.D.
Husseini K. Manji, M.D.
Oxford University

Global Therapeutic Area Head, Neuroscience

Johnson and Johnson (J&J) Pharmaceutical Research and Development

Adjunct Professor in Psychiatry and Behavioral Sciences

Scientific Council Member (Joined 2000)

1999 Falcone Prize for Outstanding Achievement in Affective Disorders Research (Colvin Prize)

1998 Independent Investigator Grant


Dr. Manji leads a preclinical and clinical global team whose broad goal is to discover and develop new therapeutics for major neurologic, psychiatric, and pain-related diseases with a high unmet need for effective treatments. Dr. Manji’s research has helped to conceptualize severe neuropsychiatric disorders as genetically influenced disorders of synaptic and neural plasticity, and led to the investigation of key novel therapeutics. The major focus of his research has been the investigation of disease- and treatment-induced changes in gene and protein networks that regulate synaptic and neural plasticity in brain and behavior disorders.

Before joining J&J, Dr. Manji was Chief, Laboratory of Molecular Pathophysiology & Experimental Therapeutics at the National Institute of Mental Health (NIMH), the largest program of its kind in the world.

Moderated by
Jeffrey Borenstein, M.D.
Brain & Behavior Research Foundation

Jeffrey Borenstein, M.D., serves as the President & CEO of the Brain & Behavior Research Foundation, the largest private funder of mental health research grants. Dr. Borenstein developed the Emmy-nominated public television program “Healthy Minds,” and serves as host and executive producer of the series. The program, broadcast nationwide, is available online, and focuses on topics in psychiatry in order to educate the public, reduce stigma and offer a message of hope. Dr. Borenstein also serves as Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association.

Dr. Borenstein is a Fellow of the New York Academy of Medicine and serves as the Chair of the Section of Psychiatry at the Academy. He also has served as the President of the New York State Psychiatric Association. Dr. Borenstein earned his undergraduate degree at Harvard and his medical degree at New York University.