“My mother was diagnosed with schizophrenia when I was a little boy. She lost custody of us. I was raised by my dad. No one even told me my mother was mentally ill. Things have changed enormously since then.” ─ Joel E....
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Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research
Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.
Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.
Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.
Groundbreaking research led by Dr. Paola Dazzan, NARSAD Young Investigator Grantee, was recently featured on the BBC prime time show “Newsnight.” This new research can predict the severity of psychosis using sophisticated...
Recent Foundation-funded research led by NARSAD Distinguished Investigator Grantee Aaron Beck, M.D. at the University of Pennsylvania, demonstrates that a targeted form of cognitive therapy can improve psychosocial and...
Upwards of half of people taking antipsychotic medications continue to have some symptoms of psychosis. Cognitive behavioral therapy (CBT) is a non-pharmaceutical intervention that helps people develop skills for coping...
Genome-wide association studies (GWAS), begun in 2005 as a coordinated international effort to search for genes associated with susceptibility for complex diseases, have yielded important findings in virtually every major...