For people with mood disorders such as bipolar disorder or major depressive disorder─complex, heterogeneous illnesses on their own─having other brain and behavior disorders at the same time is the rule rather than the...
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You are hereMental Illnesses ›
Did you know that almost 7% of the U.S. population is diagnosed with depression?
Clinical depression is a serious condition that negatively affects how a person thinks, feels, and behaves. In contrast to normal sadness, clinical depression is persistent, and significantly interferes with daily life. Untreated, symptoms can last for weeks, months, or years; and if inadequately treated, depression can lead to other health-related issues. Symptoms include: a depressed mood most of the day, every day; diminished interest in daily activities; changes in appetite and sleeping patterns; fatigue; restlessness; anxiety; feelings of worthlessness or helplessness; difficulty concentrating; increased alcohol or drug use; thoughts of death or suicide.
Leading researcher seeks to understand molecular basis of stress and resilience in the brain
One of the most remarkable facts about depression is that it remains a “syndrome” ─ a list of symptoms, as opposed to a...
A significant minority of people with depressive illness fail to respond to any currently available antidepressant medication. However, new methods of brain stimulation offer the possibility of relief from their symptoms...
Carlos A. Zarate, M.D., 2011 Outstanding Achievement in Mood Disorders Research Prizewinner, has pioneered research on rapid-acting antidepressants and their mechanism of action. One such drug is ketamine, which has been...
While most studies focus on brain and behavior disorders as cause for substance abuse (ie., self-medication), Scientific Council Member Eric Nestler, M.D., Ph.D. and colleagues have discovered how substance abuse can...