ASD

Study Reveals How High-Impact Autism Mutations Alter the Way Proteins Interact, Driving Neurodevelopmental Pathology & Pointing to New Therapeutic Targets

In important new research, researchers have added new kinds of knowledge to our understanding of how severe gene mutations that have the power to cause autism spectrum disorder (ASD) alter cell… Read More

Male-Specific Impairments Spurred by Maternal-Fetal Immune Conflicts May Account for Some of the Male Skew in Autism, New Research Suggests

Newly published research led by a BBRF grantee sheds important new light on how, during pregnancy, activation of the mother’s immune system—for example, in response to a viral infection—can set in… Read More

In Reversal of Typical Development Pattern in Adolescence, Older Autistic Youths Show Less Neural Engagement with Nonfamilial Voices, Study Finds

Newly published research by a team led by BBRF grantees finds distinct age-related patterns in children and adolescents with autism spectrum disorder (ASD) that may help explain challenges in social… Read More

Some Genetic Mutations Implicated in Autism Alter Early Brain Development Through Changes in the Regulation of Gene Expression, Study Shows

New results published in Nature from a team co-led by researchers who have received BBRF grant support mark an important step forward in the decades-long effort to connect genetic risk factors for… Read More

Study Finds Evidence of a Molecular Mechanism Underlying Altered Excitatory Neurotransmission in Autism

Using PET imaging and EEG brain recordings, investigators say they have found a potential mechanism underlying altered excitatory neurotransmission in people with autism. Read More

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