NARSAD Young Investigator Grantee, Alexander Niculescu, III, M.D., Ph.D. has led a team of scientists at the Indiana University School of Medicine in pinpointing the genes most responsible for schizophrenia. To identify and prioritize the genes reported Tuesday in the Nature journal Molecular Psychiatry, the researchers combined data from several different types of studies.
In 2001, NARSAD Distinguished Investigator Grantee, Dolores Malaspina, M.D. concluded that having an older father increases the risk of developing schizophrenia. Schizophrenia has strong genetic components, including de novo genetic mutations, and this study shows there is a higher risk of these mutations as paternal age increases. In fact, men having children over the age of 50...
In 1999, results from the Multimodal Treatment for ADHD (MTA) study - the most comprehensive study of treatment strategies for ADHD ever undertaken - were published explaining that for children with attention deficit hyperactivity disorder (ADHD), medication is a more successful treatment option than non-medication treatments such as behavioral therapy and community care....
Beginning in 1992, a longitudinal investigation known as the Great Smoky Mountain Study was conducted with approximately 1,400 children ages 9 - 16. The study, lead by NARSAD Distinguished Investigator Grantee, E. Jane Costello, Ph.D. identified key factors related to children and brain and behavior disorders. Specifically, the findings continue to help reveal which young people...
