Discoveries

Eric J. Nestler, M.D., Ph.D., Scientific Council, Mount Sinai School of Medicine
Eric J. Nestler, M.D., Ph.D.
November 15, 2011

Leading researcher seeks to understand molecular basis of stress and resilience in the brain

One of the most remarkable facts about depression is that it remains a “syndrome” ─ a list of symptoms, as opposed to a...

Keming Gao, M.D., Ph.D. of Case Medical Center
Keming Gao, M.D., Ph.D.
November 15, 2011

For people with mood disorders such as bipolar disorder or major depressive disorder─complex, heterogeneous illnesses on their own─having other brain and behavior disorders at the same time is the rule rather than the...

Eric J. Nestler, M.D., Ph.D., with members of the Nestler Lab
Eric J. Nestler, M.D., Ph.D.
November 15, 2011

A recent study by Dr. Eric Nestler’s team explored how an acquired behavior such as stress due to “social defeat” could cause behavioral changes in an individual’s offspring.  It is well known that the way a mother treats...

Sarah H. Lisanby, M.D., Duke University School of Medicine
Sarah H. Lisanby, M.D.
November 15, 2011

A significant minority of people with depressive illness fail to respond to any currently available antidepressant medication. However, new methods of brain stimulation offer the possibility of relief from their symptoms...

Jennifer Gottlieb, Ph.D., NARSAD YI, Dartmouth Medical School
Jennifer Gottlieb, Ph.D.
November 15, 2011

Upwards of half of people taking antipsychotic medications continue to have some symptoms of psychosis. Cognitive behavioral therapy (CBT) is a non-pharmaceutical intervention that helps people develop skills for coping...

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