What do you see on the horizon in the next few years as a breakthrough treatment for depression?

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Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression

Several rapidly acting antidepressants are currently in clinical trial, such as ketamine (see 2011 Highlights, Dr. Zarate, on p.2). These rapidly acting agents have novel mechanisms compared to currently available antidepressants and could offer significant improvement to patients who do not fully respond to today's medications. In addition, efforts continue to identify even more antidepressant medications with novel mechanisms of action.

 

Eric J. Nestler, M.D., Ph.D.
Scientific Council Member
Nash Family Professor of Neuroscience
Chair, Department of Neuroscience
Director, Friedman Brain Institute
Mount Sinai School of Medicine