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Did you know that schizophrenia affects more than 1 percent of the world's population?

See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

learn more about schizophrenia

Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research


Xiaodong Zhang, Ph.D. - Brain & behavior research expert on schizophrenia
Xiaodong Zhang, Ph.D.
April 13, 2015
Using a mouse model, scientists have found that the steroid pregnenolone sulfate reduces both behavioral and cognitive symptoms like those seen in...
Juan R. Bustillo, M.D. - Brain & behavior research expert on schizophrenia
Juan R. Bustillo, M.D.
April 10, 2015
A new study using brain imaging shows that people with schizophrenia have abnormalities in their white matter that correlate with psychosis, as well as...
Nathan A. Fox, Ph.D. - Brain & behavior research expert on mental illness
Nathan A. Fox, Ph.D.
April 07, 2015
A new study of Romanian orphans confined to institutions reveals that early social and emotional neglect leads to compromises in development of the brain’s...
Aristotle Voineskos, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Aristotle Voineskos, Ph.D.
April 06, 2015
A new study suggests that the neural networks (connections between brain areas) in people with a particular subtype of schizophrenia differ significantly...
Lucina Q. Uddin, Ph.D. - Brain & behavior research expert on autism
Lucina Q. Uddin, Ph.D.
April 03, 2015
Researchers have found that patterns of functional brain connectivity––the strength of connections between parts of the brain––that are unique to autism...


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