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Did you know that schizophrenia affects more than 1 percent of the world's population?

See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

learn more about schizophrenia

Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research


Cameron Carter, M.D. - Brain & Behavior Research Expert on Schizophrenia
Cameron Carter, M.D.
November 20, 2015
Researchers have used functional magnetic resonance imaging (fMRI) to gain new insights into the changes in memory and brain function associated with...
Lakshmi N. Yatham, M.D. - Brain & Behavior Research Expert on Bipolar Disorder
Lakshmi N. Yatham, M.D.
November 19, 2015
Some antipsychotic medicines commonly used to treat a type of bipolar disorder may not have clear benefits after six months of use, researchers have found....
Paul Greengard, Ph.D. - Brain & Behavior Research Expert on Depression
Paul Greengard, Ph.D.
November 13, 2015
Blocking a receptor in the brain called mGluR5 is considered a potential strategy for treating a number of disorders, including major depression, Parkinson’s...
Kerry J. Ressler, M.D., Ph.D. - Brain & Behavior Research Expert on ptsd
Kerry J. Ressler, M.D., Ph.D.
November 10, 2015
New research in mice has unlocked clues as to how MDMA — also known as the rave drug Ecstasy — can treat symptoms of post-traumatic stress disorder (PTSD)....
Michael O’Donovan, M.D., Ph.D. - Brain & Behavior Research Expert on Schizophrenia
Dr. Michael O’Donovan
November 06, 2015
Scientists who comprehensively analyzed patient data to test two different models for how schizophrenia might arise have concluded it is caused by multiple...


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