Joel E. Kleinman, M.D., Ph.D., the Foundation’s 2011 Lieber Prizewinner for Schizophrenia Research, led groundbreaking research which involved, for the first time, mapping brain development across different stages of life by changes in gene expression. The results of these studies, which involved the analysis of post-mortem brain tissue, were published in the October 26, 2011 issue of Nature Magazine. The findings shed light on the pathology and risk factors for severe mental illnesses like schizophrenia. “Ultimately, we want to find targets for treatment; this lets you take the first step in understanding how genetic variants increase risk for any brain disease,” Kleinman said.
Watch Dr. Kleinman's Outstanding Achievement Prize Video: