Did you know major depressive disorder is one of the most common mental disorders in the United States?
Almost 7% of the U.S. population is diagnosed with depression. Tweet >
Clinical depression is a serious condition that negatively affects how a person thinks, feels, and behaves. In contrast to normal sadness, clinical depression is persistent, and significantly interferes with daily life. Untreated, symptoms can last for weeks, months, or years; and if inadequately treated, depression can lead to other health-related issues. Symptoms include: a depressed mood most of the day, every day; diminished interest in daily activities; changes in appetite and sleeping patterns; fatigue; restlessness; anxiety; feelings of worthlessness or helplessness; difficulty concentrating; increased alcohol or drug use; thoughts of death or suicide.
Left images show localization of SNX27 (shown in green) and NeuN (shown in red) in the CA1 region of the hippocampus, the brain's learning and memory center. Right image shows superimposition of magnified region. (Credit: Courtesy of Kalyn Stern and Paul Slesinger, Salk Institute for Biological Studies)