Depression

Did you know major depressive disorder is one of the most common mental disorders in the United States?

Almost 7% of the U.S. population is diagnosed with depression. Tweet >

Clinical depression is a serious condition that negatively affects how a person thinks, feels, and behaves. In contrast to normal sadness, clinical depression is persistent, and significantly interferes with daily life. Untreated, symptoms can last for weeks, months, or years; and if inadequately treated, depression can lead to other health-related issues. Symptoms include: a depressed mood most of the day, every day; diminished interest in daily activities; changes in appetite and sleeping patterns; fatigue; restlessness; anxiety; feelings of worthlessness or helplessness; difficulty concentrating; increased alcohol or drug use; thoughts of death or suicide.

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Alexandre G. Dayer, M.D. - Brain & Behavior Research Expert on Depression
Alexandre G. Dayer, M.D.
October 20, 2015
In a study of mice, researchers have found that the positioning of brain cells is affected by early-life impairment of the system that regulates serotonin — a...
Yvette I. Sheline, M.D. - Brain & Behavior Research Expert on PTSD
Yvette I. Sheline, M.D.
October 16, 2015
Anxiety and depression symptoms in major depression and post-traumatic stress disorder reflect abnormal connections to the same emotion center in the brain,...
Steven J. Siegel, M.D., Ph.D. - Brain & Behavior Research Expert on Depression
Steven J. Siegel, M.D., Ph.D.
October 13, 2015
Ketamine, an anesthetic that is being tested as a fast-acting antidepressant, causes delayed social development and changes in brain function that last into...
Adolfo Sequeira, Ph.D. - Brain & Behavior Research expert on depression
Adolfo Sequeira, Ph.D.
October 09, 2015
In a new analysis, scientists have found evidence of accelerated cellular aging within the hippocampus—a brain region that processes and stores memories—in...
Madhukar H. Trivedi, M.D. - Brain & Behavior Research Expert on Depression
Madhukar H. Trivedi, M.D.
October 02, 2015
The impact of exercise on reducing excessive sleepiness in depression is linked to certain chemicals, researchers have found. Reporting their findings online...

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