I give money to NARSAD and also have an adult daughter with bipolar disorder. The self-stigma, shame and sense of failure associated with brain illnesses such as schizophrenia and bipolar disorder can not be over-estimated. It's difficult enough dealing with the ignorance, stigma and the myths of mental illness found in our society at large. Thank you, Dr. Bassett, for this importance research. I can only hope that such information is incorporated into treatment strategies.