2000 Breakthrough in Treatment for Resistant Depression

Mark George, M.D., Scientific Council Member, Expert on depression and TMS
Mark George, M.D.

With the help of a NARSAD Young Investigator Grant, Scientific Council Member Mark S. George, M.D. developed Transcranial Magnetic Stimulation (TMS), a new kind of non-invasive brain stimulation as an alternative for electroconvulsive therapy (ECT) in treatment-resistant depression. In 1995, unable to get NIH funding for TMS, a NARSAD Young Investigator Grant allowed the work to gather important clinical information and served as "bridge" funding to set the stage for the emergence of this industry. Following the initial NARSAD Young Investigator Grant, numerous NIH, Department of Defense and VA awards valued at several millions of dollars furthered development of TMS until it received FDA approval in 2008.

Learn more about Transcranial Magnetic Stimulation and Next Generation Therapies.

Read a letter written by Dr. George about the importance and impact of NARSAD Grants.

Read a scientific abstract of Dr. George's Study in The Journal of Neuropsychiatry and Clinical Neurosciences.

Read a scientific abstract of Dr. George's Study in Biological Psychiatry.

Read a scientific abstract of Dr. George's Study in The Archives of General Psychiatry.

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Please note that researchers cannot give specific recommendations or advice about treatment; diagnosis and treatment are complex and highly individualized processes that require comprehensive face-to- face assessment. Please visit our "Ask an Expert" section to see a list of Q & A with NARSAD Grantees.
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