Ask an Expert

Dr. Katherine L. Wisner, M.D., expert on post-partum depression
Q. What is the difference between ‘baby blues’ and Postpartum Depression?
A. “Distinction between a very brief, tearful, maybe anxious, uncomfortable 4 or 5 days... More >
Katherine L. Wisner, M.D.
Q. How is depression specific to or different in women?
A. “It’s the same rate of occurrence in boys and girls until puberty, when in puberty... More >
Katherine L. Wisner, M.D.
Q. What would recovery from depression look like?
A. “A woman who is back to her pre-Depression symptom level, with the ability to... More >
Bruce S. McEwen, Ph.D. - Brain and behavior research expert on depression
Q. My sister lives with depression and seems to be having increasing issues with her memory as well. You say that stress and depression can “shrink” the brain. Can antidepressants and/or other treatments reverse that?
A. Chronic depression is associated with shrinkage of brain areas that are involved in... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on depression
Q. What options do patients with treatment-resistant depression have?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression
Q. My father-in-law was treated with radiation for prostate cancer 2 years ago. Since then he seems depressed. He does not believe in therapy. What can we do? Do you think the depression could be caused by something related to his cancer treatment?
A. Depression is often seen in the context of many medical illnesses, including cancer... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on depression
Q. Why do some people respond better than others to depression treatments?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior expert on anxiety
Q. Based off your mouse studies, do you think that the majority of men who are prone to stress and anxiety are fated to have children with the same issues?
A. No. An individual’s risk for a syndrome as complex and variable as depression or... More >
Myrna Weissman, Ph.D. - Brain & behavior research expert on depression
Q. There is a history of depression in my family. But how do I know whether my teenage daughter is just moody (like lot of girls her age) or whether she’s actually depressed?
A. Here we need to differentiate between population science and individual care. On a... More >
Dr. Katherine L. Wisner, M.D., expert on post-partum depression
Q. Where will the breakthroughs come in the next 10 years in treating depressed women?
A. Dr. Wisner presented at the 2010 Palm Beach Mental Health Research Symposium. She... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on bipolar disorder
Q. Are there alternative treatments that might help people with mood disorders?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Myrna Weissman, Ph.D. - Brain & behavior research expert on depression
Q. How can I explain my depression to my third-grader? I don’t want to hurt his chances of having good mental health if he knows I’m struggling.
A. The evidence is quite strong that if you can keep yourself in remission, which may... More >
Q. What type of blood pressure medication interferes with Antidepressant LImbitrol?
A. More >
Katherine L. Wisner, M.D.
Q. How important is it to treat depression during pregnancy?
A. “A woman who is depressed in pregnancy is certainly very likely to continue to be... More >
Karl Deisseroth, M.D., Ph.D. - Brain and behavior research expert on schizophrenia
Q. Have any of the labs that are using your invention CLARITY to more precisely observe the brain after death found things that were particularly surprising in your view?
A. Though CLARITY technology is so new that these kinds of studies have not yet been... More >
Karl Deisseroth, M.D., Ph.D. - brain & behavior research expert on depression
Q. What are some recent advancements that have been made in depression research?
A. Karl Deisseroth, M.D., Ph.D., of Stanford University received the Goldman-Rakic... More >
Myrna Weissman, Ph.D. - Brain & behavior research expert on depression
Q. Why does the incidence of depression go up after puberty? Is it because of hormones?
A. There are good population-based data showing that the onset of depression increases... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression
Q. What do you see on the horizon in the next few years as a breakthrough treatment for depression?
A. Several rapidly acting antidepressants are currently in clinical trial, such as... More >
Robert C. Malenka, M.D., Ph.D. - Brain & behavior research expert on depression
Q. Your work is fascinating. It is frightening to think about neurotransmitters in the brain being manipulated to reduce or eliminate depressed behaviors. How do you foresee these malfunctions in brain circuitry and synaptic connections being treated?
A. The hope of all neuroscience researchers is that by defining the malfunctions in... More >
Karl Deisseroth, M.D., Ph.D. - Brain and behavior research expert on schizophrenia
Q. Can you envision ways in which the optogenetics technology that you invented might eventually improve the design or use of psychiatric medications?
A. The major challenge we face in psychiatry is understanding. Psychiatric disease... More >
Kerry Ressler, M.D., Ph.D. - Brain & behavior research expert on ptsd
Q. What happens if someone has “blocked out” the specifics of a trauma—or it happened so long ago that the details are fuzzy—but they have the behavioral symptoms of PTSD? Is it still possible to treat them?
A. Yes, they will still respond to pharmacotherapy. Right now, SSRIs remain the first... More >
John H. Krystal, M.D.
Q. September 11th is a traumatic date – what do you recommend to manage the stress?
A. It is true that we seem to be bombarded with news related to disasters and social... More >
John H. Krystal, M.D.
Q. Where will the breakthroughs come in treating PTSD?
A. “Uniting molecular genetics with brain imaging and psychopharmacology - these sorts... More >
John H. Krystal, M.D.
Q. What would 'recovery' of PTSD look like?
A. “To be resilient to things they were having trouble coping with … What treatment... More >

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