Ask an Expert

Judith L. Rapoport, M.D. - Brain & behavior research expert on schizophrenia
Q. What are the most promising areas of research today—and how close are we getting to prevention and cures?
A. Certainly, brain imaging and genetics have the greatest attention in clinical... More >
Jay N. Giedd, M.D. - brain & behavior research expert on schizophrenia
Q. How common is childhood-onset schizophrenia? What advice can you give a parent?
A. Jay N. Giedd, M.D. of the National Institute of Mental Health received the Ruane... More >
Bryan L. Roth, M.D., Ph.D.
Q. How does a personal connection to mental illness impact the work you do?
A. I’m reminded on a daily basis how far we’ve come and yet how far we need to go to... More >
Daniel Wolf, MD. PhD. - Assoc. Prof. Psychiatry, Perelman School of Medicine
Q. What are negative symptoms of schizophrenia?
A. "I use functional neuroimaging primarily as a method to study this...allows us to... More >
Jay N. Giedd, M.D. - brain & behavior research expert on schizophrenia
Q. How common is relapse after stabilization in schizophrenia?
A. Jay N. Giedd, M.D. of the National Institute of Mental Health received the Ruane... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Judith L. Rapoport, M.D. - Brain & behavior research expert on schizophrenia
Q. Is there any way to prevent suspect genes from causing mental illness or to prevent the development of these 'copy-number variants' (CNVs) that have been linked to schizophrenia? Is that a current focus of research?
A. So far, there is no known way to stop copy number variants (CNVs) from forming. But... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is Bipolar Disorder inheritable?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Husseini K. Manji, M.D.
Q. Can anti-seizure medications effectively treat bipolar II disorder?
A. It’s difficult to say without seeing the specific patient involved. As is the case... More >
Husseini K. Manji, M.D.
Q. Is Ketamine a possible treatment option for bipolar?
A. Ketamine is an experimental treatment for mental health conditions and is not... More >
Robert C. Malenka, M.D., Ph.D. - Brain & behavior research expert on bipolar disorder
Q. Our son lives with bipolar disorder and takes 1,000 mg of Depakote® daily. It doesn’t seem to be working; he remains unmotivated and very anxious. He feels no need to seek therapy do you have any advice on how to get someone to visit a therapist?
A. Helping a friend or loved one understand that they will benefit greatly from seeing... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is there a chance that I could pass Bipolar Disorder on to my child?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on bipolar disorder
Q. Are there alternative treatments that might help people with mood disorders?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is there a test to diagnose Bipolar Disorder?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Q. Four generations of family, possibly five, have a history that includes severe mental illness. This is not a matter of nurture as we were all raised separately. How common is this? I have chosen to not have children due to this legacy.
A. Unfortunately, this is not uncommon, since all forms of severe mental illness are... More >
Husseini K. Manji, M.D.
Q. What will the breakthroughs be in treatment for mood disorders in the next 5 years?
A. The world of neuroscience really is exploding, and I like to say that this is a... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression
Q. What do you see on the horizon in the next few years as a breakthrough treatment for depression?
A. Several rapidly acting antidepressants are currently in clinical trial, such as... More >
Husseini K. Manji, M.D.
Q. What advice do you offer for comorbidity (diagnosed with more than one mental illness)?
A. Many people have more than one official diagnosis in mental health, such as... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on bipolar disorder
Q. Are there alternative treatments that might help people with mood disorders?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Katherine L. Wisner, M.D.
Q. How important is it to treat depression during pregnancy?
A. “A woman who is depressed in pregnancy is certainly very likely to continue to be... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on depression
Q. Why do some people respond better than others to depression treatments?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior expert on anxiety
Q. Based off your mouse studies, do you think that the majority of men who are prone to stress and anxiety are fated to have children with the same issues?
A. No. An individual’s risk for a syndrome as complex and variable as depression or... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on depression
Q. What options do patients with treatment-resistant depression have?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Katherine L. Wisner, M.D.
Q. How is depression specific to or different in women?
A. “It’s the same rate of occurrence in boys and girls until puberty, when in puberty... More >

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