Ask an Expert

Jay N. Giedd, M.D. - brain & behavior research expert on schizophrenia
Q. How common is childhood-onset schizophrenia? What advice can you give a parent?
A. Jay N. Giedd, M.D. of the National Institute of Mental Health received the Ruane... More >
Judith L. Rapoport, M.D., expert on schizophrenia
Q. Do you recommend finding out if your children carry the risk genes that can predispose to different mental illnesses? Is it better to know―and if so, what does one do with that information?
A. There are genes in general which so far have not been helpful to measure in most... More >
Marc G. Caron, Ph.D. - brain & behavior research expert on schizophrenia
Q. Is there any evidence linking stress to schizophrenia?
A. Marc G. Caron, Ph.D., of the Duke University Medical Center received the Lieber... More >
Daniel Wolf, MD. PhD. - Assoc. Prof. Psychiatry, Perelman School of Medicine
Q. What are negative symptoms of schizophrenia?
A. "I use functional neuroimaging primarily as a method to study this...allows us to... More >
Marc G. Caron, Ph.D. - brain & behavior research expert on schizophrenia
Q. How likely is it for schizophrenia to be passed along to later generations?
A. Marc G. Caron, Ph.D., of the Duke University Medical Center received the Lieber... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Schahram Akbarian, M.D., Ph.D. Scientific Council Member 1993, 2000 NARSAD Young Investigator Grantee 1997 Klerman Prizewinner Professor of Psychiatry and Neuroscience Chief of the Division of Psychiatric Epigenomics Mount Sinai School of Medicine, expert on schizophrenia
Q. There are endless genetic studies for mental illness and yet the treatments don’t seem to be getting better. Why is there still such an emphasis on understanding the genetics?
A. This is an excellent question. Once a disease-associated gene has been found,... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on bipolar disorder
Q. Are there alternative treatments that might help people with mood disorders?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Husseini K. Manji, M.D.
Q. Can anti-seizure medications effectively treat bipolar II disorder?
A. It’s difficult to say without seeing the specific patient involved. As is the case... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is there a chance that I could pass Bipolar Disorder on to my child?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Robert C. Malenka, M.D., Ph.D. - Brain & behavior research expert on bipolar disorder
Q. Our son lives with bipolar disorder and takes 1,000 mg of Depakote® daily. It doesn’t seem to be working; he remains unmotivated and very anxious. He feels no need to seek therapy do you have any advice on how to get someone to visit a therapist?
A. Helping a friend or loved one understand that they will benefit greatly from seeing... More >
Husseini K. Manji, M.D.
Q. What advice do you offer for comorbidity (diagnosed with more than one mental illness)?
A. Many people have more than one official diagnosis in mental health, such as... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is Bipolar Disorder inheritable?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is there a test to diagnose Bipolar Disorder?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Q. Four generations of family, possibly five, have a history that includes severe mental illness. This is not a matter of nurture as we were all raised separately. How common is this? I have chosen to not have children due to this legacy.
A. Unfortunately, this is not uncommon, since all forms of severe mental illness are... More >
Husseini K. Manji, M.D.
Q. Is Ketamine a possible treatment option for bipolar?
A. Ketamine is an experimental treatment for mental health conditions and is not... More >
Husseini K. Manji, M.D.
Q. What will the breakthroughs be in treatment for mood disorders in the next 5 years?
A. The world of neuroscience really is exploding, and I like to say that this is a... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression
Q. What do you see on the horizon in the next few years as a breakthrough treatment for depression?
A. Several rapidly acting antidepressants are currently in clinical trial, such as... More >
Robert C. Malenka, M.D., Ph.D. - Brain & behavior research expert on depression
Q. Your work is fascinating. It is frightening to think about neurotransmitters in the brain being manipulated to reduce or eliminate depressed behaviors. How do you foresee these malfunctions in brain circuitry and synaptic connections being treated?
A. The hope of all neuroscience researchers is that by defining the malfunctions in... More >
Dr. Katherine L. Wisner, M.D., expert on post-partum depression
Q. What is the difference between ‘baby blues’ and Postpartum Depression?
A. “Distinction between a very brief, tearful, maybe anxious, uncomfortable 4 or 5 days... More >
Katherine L. Wisner, M.D.
Q. How important is it to treat depression during pregnancy?
A. “A woman who is depressed in pregnancy is certainly very likely to continue to be... More >
Bruce S. McEwen, Ph.D. - Brain and behavior research expert on depression
Q. My sister lives with depression and seems to be having increasing issues with her memory as well. You say that stress and depression can “shrink” the brain. Can antidepressants and/or other treatments reverse that?
A. Chronic depression is associated with shrinkage of brain areas that are involved in... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on depression
Q. What options do patients with treatment-resistant depression have?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on bipolar disorder
Q. Are there alternative treatments that might help people with mood disorders?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >

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