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Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Q. Is there a viral or infection component to schizophrenia that could be treated with an antiviral or an antibiotic, especially at first episode?
A. This remains an area of active research. There is currently no definitive evidence... More >
Jeffrey A. Lieberman, M.D., Columbia University Medical Center
Q. What is ‘recovery’ for a patient with Schizophrenia?
A. “They have an illness, they may continue to have some level of symptoms, but it’s... More >
Judith L. Rapoport, M.D. - Brain & behavior research expert on schizophrenia
Q. What are the most promising areas of research today—and how close are we getting to prevention and cures?
A. Certainly, brain imaging and genetics have the greatest attention in clinical... More >
Jay N. Giedd, M.D. - brain & behavior research expert on schizophrenia
Q. How common is childhood-onset schizophrenia? What advice can you give a parent?
A. Jay N. Giedd, M.D. of the National Institute of Mental Health received the Ruane... More >
Huda Akil, Ph.D. - Brain & behavior research expert on depression
Q. In your work with the Pritzker Neuropsychiatric Research Consortium, have you uncovered any new genes that you think might be related to mental illnesses besides major depression?
A. Yes, the Pritzker Consortium is interested in three severe psychiatric disorders—... More >
Marc G. Caron, Ph.D. - brain & behavior research expert on schizophrenia
Q. How likely is it for schizophrenia to be passed along to later generations?
A. Marc G. Caron, Ph.D., of the Duke University Medical Center received the Lieber... More >
Patrick F. Sullivan, M.D., FRANZCP - Brain & behavior research expert on schizophrenia
Q. My husband’s sister has schizophrenia and I’m afraid that if we have children they could be affected too. How high is the risk of this happening?
A. In general, large and carefully conducted studies tell us that the absolute risk is... More >
Daniel Wolf, MD. PhD. - Assoc. Prof. Psychiatry, Perelman School of Medicine
Q. What are negative symptoms of schizophrenia?
A. "I use functional neuroimaging primarily as a method to study this...allows us to... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Bryan Roth, M.D., Ph.D.
Q. How long will it take to get real improvements in treatment for illnesses like schizophrenia?
A. There are several novel medications in both early- and later-stage clinical... More >
Huda Akil, Ph.D. - Brain & behavior research expert on depression
Q. In your work with the Pritzker Neuropsychiatric Research Consortium, have you uncovered any new genes that you think might be related to mental illnesses besides major depression?
A. Yes, the Pritzker Consortium is interested in three severe psychiatric disorders—... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Q. Four generations of family, possibly five, have a history that includes severe mental illness. This is not a matter of nurture as we were all raised separately. How common is this? I have chosen to not have children due to this legacy.
A. Unfortunately, this is not uncommon, since all forms of severe mental illness are... More >
Husseini K. Manji, M.D.
Q. What advice do you offer for comorbidity (diagnosed with more than one mental illness)?
A. Many people have more than one official diagnosis in mental health, such as... More >
Husseini K. Manji, M.D.
Q. Can anti-seizure medications effectively treat bipolar II disorder?
A. It’s difficult to say without seeing the specific patient involved. As is the case... More >
Husseini K. Manji, M.D.
Q. Is Ketamine a possible treatment option for bipolar?
A. Ketamine is an experimental treatment for mental health conditions and is not... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression
Q. What do you see on the horizon in the next few years as a breakthrough treatment for depression?
A. Several rapidly acting antidepressants are currently in clinical trial, such as... More >
Husseini K. Manji, M.D.
Q. What will the breakthroughs be in treatment for mood disorders in the next 5 years?
A. The world of neuroscience really is exploding, and I like to say that this is a... More >
Robert C. Malenka, M.D., Ph.D. - Brain & behavior research expert on bipolar disorder
Q. Our son lives with bipolar disorder and takes 1,000 mg of Depakote® daily. It doesn’t seem to be working; he remains unmotivated and very anxious. He feels no need to seek therapy do you have any advice on how to get someone to visit a therapist?
A. Helping a friend or loved one understand that they will benefit greatly from seeing... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on bipolar disorder
Q. Are there alternative treatments that might help people with mood disorders?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is there a test to diagnose Bipolar Disorder?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is Bipolar Disorder inheritable?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is there a chance that I could pass Bipolar Disorder on to my child?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Huda Akil, Ph.D. - Brain & behavior research expert on depression
Q. Your description of a “depressed brain” was very interesting. Has anyone ever looked at the brains of people after they’ve been treated for depression for several years—does treatment change the way the brain looks?
A. This is an excellent question and one that we have thought about and begun to... More >
Karl Deisseroth, M.D., Ph.D. - Brain and behavior research expert on schizophrenia
Q. Can individuals volunteer to be part of the BRAIN Initiative? I’d be interested in having my brain scanned and mapped.
A. Though the programs that will be funded by the BRAIN initiative have not yet been... More >

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