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Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Akira Sawa, M.D., Ph.D. expert on anxiety
Akira Sawa, M.D., Ph.D.
April 18, 2013

With the support of a NARSAD Distinguished Investigator Grant, a team of neuroscientists at the Johns Hopkins University School of Medicine has discovered a biological mechanism that helps explain the long mysterious...

Stamatia Pappas
Stamatia Pappas
April 18, 2013

A family credits recovery from schizoaffective disorder to relatively early intervention, the right medication, never losing hope and a great therapist

Recalling her son’s last year in high school, Stamatia Pappas...

Judith L. Rapoport, M.D., expert on schizophrenia
Judith L. Rapoport, M.D.
April 18, 2013

Interview With A Researcher: Chief of Child Psychiatry at the NIMH Shares Insight

Learning how genes predispose, even if they don’t determine

Over the last decade of her distinguished career in studying...

Jordan W. Smoller, M.D., Sc.D. expert in mental health research
Jordan W. Smoller, M.D., Sc.D.
April 18, 2013

The Cross-Disorder Group of the Psychiatric Genomics Consortium (PGC), a consortium of geneticists and neuroscientists, has released the results of a worldwide, six-year-long collaboration in the first genome-wide search...

David Shaffer, M.D.
David Shaffer, M.D.
April 18, 2013

When he first heard about it in the late 1970s, David Shaffer, M.D., remembers being not only “skeptical” but in a state of disbelief. Just as his career in psychiatry was getting under way, an important study found that...

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