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Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Aaron T. Beck, M.D.
Aaron T. Beck, M.D.
October 06, 2011

Dr. Aaron T. Beck, Foundation Distinguished Investigator, invented cognitive behavioral therapy decades ago and now demonstrates that it can successfully treat the ‘negative’ symptoms of schizophrenia, such as emotional...

Z. Josh Huang, Ph.D.
Z. Josh Huang, Ph.D.
October 03, 2011

Z. Josh Huang, Ph.D. and colleagues spent portions of the last five years developing a toolkit to identify and track a highly specific, vital group of brain cells that are linked to schizophrenia and autism. This is even...

Jason Tennies, Playing the Guitar, schizophrenia
Jason Tennies
September 30, 2011

We are Dave and Linda Tennies. One year ago on September 20, 2010, our son Jason Tennies suffered what we later identified as a severe schizophrenic break. He became delusional, suffered from hallucinations and displayed...

Jonathan Mill, Ph.D.
Jonathan Mill, Ph.D.
September 26, 2011

Jonathan Mill, Ph.D., 2009 NARSAD Young Investigator Grantee and colleagues have demonstrated that potentially reversible epigenetic changes play a key role in mental illness. 'Our findings suggest that it is not only...

Ken Harrison NARSAD
Ken Harrison
September 22, 2011

My name is Ken Harrison and like so many of you, I know first-hand the challenges of caring for a loved one with mental illness. And while each of us faces unique issues, the need for better treatments and therapies is...

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