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Did you know that schizophrenia affects more than 1 percent of the world's population?

See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

learn more about schizophrenia

Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research


2010 NARSAD Young Investigator Grantee, Thomas L. Kash, Ph.D., of the University of North Carolina, Chapel Hill, expert on anxiety and other disorders
Thomas L. Kash, Ph.D.
December 17, 2012
Alcoholism and anxiety disorders are not only among the most common brain and behavior disorders; frequently, they occur in the same individuals. The leading...
2005 NARSAD Young Investigator Grantee, Christine I. Hooker, Ph.D., now an Associate Professor in Psychology at Harvard, expert on schizophrenia
Christine I. Hooker, Ph.D.
December 17, 2012
Schizophrenia-associated deficits in cognition are not substantially improved by medication, but have been shown to improve with remedial cognitive training....
Edi Guyton, lives with depression
Edi Guyton
December 17, 2012
A woman explains why she finally agreed to try deep brain stimulation for her depression. As a Ph.D. who rose to head a university department, and as a wife...
Scientific Council Member Karl Deisseroth, M.D., Ph.D. and NARSAD Young Investigator Grantee Melissa R. Warden, Ph.D. of Stanford University, Experts in Optogenetics and Depression
Karl Deisseroth, M.D., Ph.D.
December 12, 2012
A team of neuroscientists led by NARSAD Young Investigator Grantee and Scientific Council Member Karl Deisseroth, M.D., Ph.D., has demonstrated for the first...
Carmine M. Pariante, M.D., Ph.D., Professor of Biological Psychiatry at King’s College London’s Institute of Psychiatry, expert on depression
Carmine M. Pariante, M.D., Ph.D.
December 11, 2012
Carmine M. Pariante, M.D., Ph.D., Professor of Biological Psychiatry at King’s College London’s Institute of Psychiatry, is one of the authors of a new study...


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