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Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Daniela Kaufer, Ph.D., of University of California, Berkeley, an expert in anxiety
Daniela Kaufer, Ph.D.
April 19, 2013

Occasional stress may actually have a positive impact on the brain according to a new study by lead author Daniela Kaufer, Ph.D., a Brain & Behavior Research Foundation 2009 NARSAD Young Investigator Grantee, and...

Rachel Loewy, Ph.D. - Brain and Behavior research expert on Schizophrenia
Rachel Loewy, Ph.D.
April 18, 2013

The changes to brain function that schizophrenia effects, the cognitive deficits that inflict the most devastating long-term disabilities, are difficult to reverse and can worsen with recurring psychotic episodes. Recent...

Rachel G. Klein, Ph.D. - Brain and Behavior Research expert on ADHD
Rachel G. Klein, Ph.D.
April 18, 2013

Attention-deficit hyperactivity disorder (ADHD) is the most commonly diagnosed
neurobehavioral disorder in children, but its diagnosis has been controversial.
Without specific biological markers, diagnosing...

Marina Picciotto, Ph.D. - Brain and behavior research expert on depression
Marina Picciotto, Ph.D.
April 18, 2013

Marina Picciotto, Ph.D., leading a team of researchers at Yale University, has made an exciting discovery in the search for the biological causes of depression and anxiety. Their discovery points to the importance of a...

J. John Mann, M.D. - Brain and behavior research expert on depression, bipolar disorder, and suicide
J. John Mann, M.D.
April 18, 2013

Roughly 36,000 Americans kill themselves every year. Is it possible to develop better ways to predict and avert suicide? J. John Mann, M.D., believes the answer is “yes.”  

Dr. Mann is a pioneer in the study of...

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