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Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Florin Dolcos, Ph.D., Expert on Anxiety
Florin Dolcos, Ph.D.
May 31, 2013

Do you know someone who tends to focus on the negative and bottle up emotions? A new study by NARSAD Grantee Florin Dolcos, Ph.D., and colleagues at the University of Illinois, Urbana–Champaign (UIUC), reveals that the...

Lin Mei, M.D., Ph.D., Expert on schizophrenia
Lin Mei, M.D., Ph.D.
May 30, 2013

A new study by Brain & Behavior Research Foundation NARSAD Grantees Lin Mei, M.D., Ph.D., Dong-Min Yin, Ph.D., and Graham Bean, Ph.D., of the Medical College of Georgia and their colleagues found that when they...

James W. Murrough, M.D. - expert on depression
James W. Murrough, M.D.
May 28, 2013

Preliminary results by Brain & Behavior Research Foundation NARSAD Young Investigator Grantee James W. Murrough, M.D.―in the largest clinical trial of ketamine for resistant depression to date―confirm the promise of...

Jun Z. Li, Ph.D., University of Michigan, depression expert
Jun Z. Li, Ph.D.
May 23, 2013
New Brain & Behavior Research Foundation-supported research finds evidence of altered “circadian rhythms” (the biological 24-hour clock that governs the function of every cell in our body) in the brain of people with...
perineuronal net, schizophrenia research
perineuronal nets
May 21, 2013

Brain cells suspected to malfunction in schizophrenia are surrounded by a tight-fitting molecular matrix. The exact role of this coating (or “perineuronal net”) was the focus of a study by Brain & Behavior Research...

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