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Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

NARSAD Grantee Tsuyoshi Miyakawa, Ph.D., , expert on schizophrenia, at the Institute for Comprehensive Medical Science, Fujita Health University and the National Institute for Physiological Sciences, Japan
Tsuyoshi Miyakawa, Ph.D.
February 12, 2013

Researchers have discovered a protein deficiency that results in mild chronic brain inflammation and is thought to lead to schizophrenia-related symptoms, such as working memory deficits, self-neglect, decreased social...

Hongjun Song, Ph.D., Johns Hopkins University School of Medicine, Expert on Depression
Hongjun Song, Ph.D.
February 11, 2013

Building on findings from stem cell research in 2011 that helped explain how the brain can regenerate, NARSAD Grantees performed a sophisticated series of experiments and analyses that led them to discover a protein that...

John L. R. Rubenstein, M.D., Ph.D., Brain Researcher, expert in schizophrenia and autism
John Rubenstein, M.D., Ph.D.
February 07, 2013

Collaborating researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have developed an atlas of the brain’s “gene enhancers” (or regulators) in the cerebrum and made it...

NARSAD Grantee John A. Wemmie, M.D., Ph.D., neuroscientist, University of Iowa, Expert on panic disorders and other Anxiety Disorders
John A. Wemmie, M.D., Ph.D.
February 04, 2013

The unexpected outcome of research by NARSAD Grantee John A. Wemmie, M.D., Ph.D., neuroscientist, University of Iowa and his colleagues, has implications for the future study and treatment of people with panic disorders....

Brain & Behavior Research Foundation NARSAD Distinguished Investigator Grantee Lin Mei, M.D., Ph.D. of Georgia Regents University, expert on schizophrenia
Lin Mei, M.D., Ph.D.
February 01, 2013

Brain & Behavior Research Foundation NARSAD Distinguished Investigator Grantee Lin Mei, M.D., Ph.D. of Georgia Regents University and colleagues have identified an early step in how the brain's inhibitory cells get...

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